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磁共振成像  2024年7月第15卷第7期  Chin J Magn Reson Imaging, Jul, 2024, Vol. 15, No. 7   临床研究||Clinical Articles




































              图 1 男,41岁,无 KOA组 IPFP感兴趣区勾画示意图。1A:矢状位 IDEAL-IQ图,白色区域为勾画的感兴趣区。1B:矢状位 IDEAL-IQ伪彩图,白色区域为勾
              画的感兴趣区。1C:矢状位 T2 mapping 图,紫色区域为勾画的感兴趣区。1D:矢状位 T2 mapping 图,紫色区域为勾画的感兴趣区。FF 值为 77.41%,T2 值为
              80.910 ms。图 2 女,62岁,轻度 KOA组 IPFP感兴趣区勾画示意图。2A:矢状位 IDEAL-IQ图,白色区域为勾画的感兴趣区。2B:矢状位 IDEAL-IQ伪彩图,
              白色区域为勾画的感兴趣区。2C:矢状位 T2 mapping 图,紫色区域为勾画的感兴趣区。2D:矢状位 T2 mapping 图,紫色区域为勾画的感兴趣区。FF 值为
              68.37%,T2 值为 82.875 ms。图 3 女,85 岁,重度 KOA 组 IPFP 感兴趣区勾画示意图。3A:矢状位 IDEAL-IQ 图,白色区域为勾画的感兴趣区。3B:矢状位
              IDEAL-IQ 伪彩图,白色区域为勾画的感兴趣区。3C:矢状位 T2 mapping 图,紫色区域为勾画的感兴趣区。3D:矢状位 T2 mapping 图,紫色区域为勾画的感
              兴趣区。FF值为62.07%,T2值为90.710 ms。KOA:膝骨关节炎;IPFP:髌下脂肪垫;IDEAL-IQ:非对称回波的最小二乘估算法迭代水脂分离。
              Fig. 1 Male, 41 years old, No KOA group, schematic diagram outlining the region of interest in the IPFP. 1A: Sagittal IDEAL-IQ image with delineated region of interest
              shows in white. 1B: Sagittal IDEAL-IQ pseudocolor image with delineated region of interest shows in white. 1C: Sagittal T2 mapping image with delineated region of
              interest shows in purple. 1D: Sagittal T2 mapping image with delineated region of interest shows in purple. FF value is 77.41%, T2 value is 80.910 ms. Fig. 2 Female, 62
              years old, mild KOA group, schematic diagram outlining the region of interest in the IPFP. 2A: Sagittal IDEAL-IQ image with delineated region of interest shows in white.
              2B: Sagittal IDEAL-IQ pseudocolor image with delineated region of interest shows in white. 2C: Sagittal T2 mapping image with delineated region of interest shows in
              purple. 2D: Sagittal T2 mapping image with delineated region of interest shows in purple. FF value is 68.37%, T2 value is 82.875 ms. Fig. 3 Female, 85 years old, severe
              KOA group, schematic diagram outlining the region of interest in the IPFP. 3A: Sagittal IDEAL-IQ image with delineated region of interest shows in white. 3B: Sagittal
              IDEAL-IQ pseudocolor image with delineated region of interest shows in white. 3C: Sagittal T2 mapping image with delineated region of interest shows in purple. 3D:
              Sagittal T2 mapping image with delineated region of interest shows in purple. FF value is 62.07%, T2 value is 90.710 ms. KOA: knee osteoarthritis; IPFP: infrapatellar fat
              pad; IDEAL-IQ: iteraterative decomposition of water and fat with echo asymmetry and least-squares estimation quantitation.

              2 结果                                                 2.2 各定量参数组间一致性
              2.1 一般资料                                                 两名放射科医师测量 IPFP 的 FF 值和 T2 值的
                  共纳入99例受检者,年龄41~85(61±10)岁,其中                     ICC 值分别为 0.97(95% CI:0.96~0.98)和 0.908(95%
              男 34 例,女 65 例,入组受检者的基本临床资料详见                         CI:0.86~0.94),一致性均较好。
              表 1。不同程度 KOA三组的年龄、IPFP FF值和 T2值                      2.3 IPFP FF值和T2值与KOA严重程度的相关性
              差异均有统计学意义(P<0.001),三组间性别、BMI                             KOA 严重程度与 IPFP 的 FF 值呈显著负相关
              差异无统计学意义(P=0.578、0.993)。                            (r= −0.779,P<0.001),而 与 T2 值 呈 显 著 正 相 关(r=

                                              表1  临床资料及各定量参数检测结果与比较
                             Tab. 1  The clinical data and the comparison of various quantitative parameters detection results
                            特征            无KOA(n=39)    轻度KOA(n=35)    重度KOA(n=25)    统计量      P值
                            年龄/岁             55±8           64±8          66±10      15.703 ①  <0.001
                            性别(男/女)/例        14/25          10/25         10/15       1.098 ②  0.578
                                   −2
                            BMI/(kg•m )     25.92±2.75    25.89±3.05     25.97±2.30   0.070 ①  0.993
                            FF/%            73.13±3.98    67.42±2.25     61.92±3.24  91.454 ①  <0.001
                            T2/ms        81.04 (79.61, 82.44)  82.72 (81.44, 84.46)  86.79 (85.32, 89.12)  47.116 ③  <0.001
                            KLG-0/例            8             0              0          —        —
                            KLG-1/例           31             0              0          —        —
                            KLG-2/例            0             35             0          —        —
                            KLG-3/例            0             0             21          —        —
                            KLG-4/例            0             0              4          —        —
                                         2
                                            ③
                                     ②
                             注:为F值;为χ 值;为H值。KOA为膝骨关节炎;KLG为Kellgren-Lawrence分级;FF为脂肪分数。
                               ①
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